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Major Clinical Depression

Major clinical depression is marked by a depressed mood most of the day, particularly in the morning, and a loss of interest in normal activities and relationships — symptoms that are present every day for at least 2 weeks. Other symptoms might include: fatigue or loss of energy almost every day, feelings of worthlessness or guilt almost every day, impaired concentration, indecisiveness, insomnia or hypersomnia (excessive sleeping) almost every day, markedly diminished interest or pleasure in almost all activities nearly every day (called anhedonia, this symptom can be indicated by reports from significant others), restlessness or feeling slowed down, recurring thoughts of death or suicide or significant weight loss or gain.

Major Depression (Clinical Depression), WebMD, https://www.webmd.com/depression/guide/major-depression#1

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