Adult Growth Hormone Deficiency (GHD) is a multifactorial disorder in which pituitary dysfunction associated with pituitary adenomas or their treatment plays a major role. Adults with GHD can have a variety of signs and symptoms, which include abnormality body composition with increased fat mass (especially central adiposity), decreased lean muscle mass, extracellular fluid volume, diminished muscle strength, physical energy and stamina, lack of motivation, lethargy, lability (changes in mood), depression, and impairment of cognitive functions.
Signs and Symptoms of Adult Growth Hormone Deficiency. Human Growth Foundation. http://hgfound.org/resources/adult-growth-hormone-deficiency/signs-and-symptoms-of-adult-growth-hormone-deficiency/